Life from an RNA World: the ancestor within
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چکیده
منابع مشابه
Life from an RNA World
platelet serotonin levels. Curiously, both groups of rats differ noticeably from their wild-type counterparts only when confronted with an environmental or pharmacological challenge. The book then goes on to describe the interaction between the serotonin system and other neurotransmitters, particularly dopamine, in models of drug reward. Primates, like humans, have complex social lives yet can ...
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A little-noted result of the confirmation of multiple premises of the RNA-world hypothesis is that we now know something about the dawn organisms that followed the origin of life, perhaps over 4 billion years ago. We are therefore in an improved position to reason about the biota just before RNA times, during the era of the first replicators, the first Darwinian creatures on Earth. An RNA conge...
متن کاملAncestral RNA: the RNA biology of the eukaryotic ancestor.
Our knowledge of RNA biology within eukaryotes has exploded over the last five years. Within new research we see that some features that were once thought to be part of multicellular life have now been identified in several protist lineages. Hence, it is timely to ask which features of eukaryote RNA biology are ancestral to all eukaryotes. We focus on RNA-based regulation and epigenetic mechani...
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A popular theory of life's origins states that the first biocatalysts were not made of protein but were made of RNA or a very similar polymer. Experiments are beginning to confirm that the catalytic abilities of RNA are compatible with this 'RNA world' hypothesis. For example, RNA can synthesize short fragments of RNA in a template-directed fashion and promote formation of peptide, ester and gl...
متن کاملTom Cech: New life beyond the RNA World
To hear Tom Cech tell it, he came by his prodigious success — Nobel Prize at 41, presidency of the Howard Hughes Medical Institute (HHMI) this year at 52 — thanks to lots of help from his friends. His 1982 discovery that RNA could behave like an enzyme and splice itself led to the 1989 Nobel in chemistry, which he shared with Sidney Altman. But he says he stumbled into the RNA World — then a sm...
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ژورنال
عنوان ژورنال: Trends in Evolutionary Biology
سال: 2010
ISSN: 2036-265X,2036-2641
DOI: 10.4081/eb.2010.e5